Weight-Loss Therapies

Phentermine Combination Therapy: How It Works|Benefits|Safety

Mechanism of Action
At Rolling Wellness, we do not offer standard Phentermine. Instead, we prescribe Phentermine in carefully compounded dual-acting combinations with either low-dose Naltrexone or Topiramate. This advanced approach enhances weight-loss results while improving long-term tolerability.

• Phentermine works as an appetite suppressant by stimulating the central nervous system to release norepinephrine, reducing hunger and boosting energy.

• Naltrexone (low dose) helps regulate cravings, supports mood stability, and reduces the reward response to overeating.

• Topiramate (low dose) helps control emotional or binge eating while improving satiety and appetite control.

Together, these combinations create a synergistic effect, making therapy more effective than Phentermine alone.

Benefits of Phentermine Combination Therapy

• Dual action helps patients achieve greater appetite control and reduced cravings

• Provides more sustainable results compared to Phentermine monotherapy

• Boosts energy and focus, supporting exercise and lifestyle changes

• Helps patients overcome weight-loss resistance or plateaus

• Customized options (with Naltrexone or Topiramate) based on individual needs and tolerability

• Well-suited to kickstart a weight loss program or losing a few pounds for an event (typically short course dosing over 3 months)

Possible Common Side Effects
Side effects may vary depending on the chosen combination, but the most commonly reported include:

• Dry mouth

• Insomnia or restlessness

• Mild increase in heart rate or blood pressure

• Constipation

• Mood or taste changes (more likely with Topiramate)

Your provider will determine which combination is best suited to your health profile.

Who Should Not Use Phentermine Combination Therapy (Contraindications)
This treatment is not appropriate for patients who have:

• History of heart disease, uncontrolled high blood pressure, or arrhythmias

• Glaucoma or uncontrolled thyroid disease

• History of drug misuse or dependence

• Pregnancy or breastfeeding

• Known hypersensitivity to Phentermine, Naltrexone, or Topiramate

*Patients must have a yearly in-office consultation with a provider to receive this medication. Currently available only in Nevada, other states TBA.*

Pricing:

$159 (30 days)

Phentermine/Naltrexone (37.5/1 mg)

Phentermine/Topiramate (10/50 mg)

7-Keto DHEA Therapy: How It Works | Benefits | Safety

Mechanism of Action
At Rolling Wellness, we offer 7-Keto DHEA, a naturally occurring metabolite of DHEA that is specifically designed to boost metabolism without converting into sex hormones like estrogen or testosterone. This makes it a safer and more targeted option for weight management.

• 7-Keto DHEA increases thermogenesis, the process by which your body burns calories to produce heat. By enhancing thyroid activity and metabolic rate, it helps your body use stored fat more efficiently.

• Unlike stimulant-based weight-loss medications, 7-Keto DHEA works gently to support fat burning while preserving lean muscle and energy.

Benefits of 7-Keto DHEA Therapy

• Boosts metabolic rate and supports calorie burning

• Targets stubborn fat areas resistant to diet and exercise

• Non-hormonal, non-stimulant option safe for both men and women

• Helps preserve lean muscle during weight-loss programs

• May support healthy energy levels and mood balance

Possible Common Side Effects
7-Keto DHEA is generally well tolerated. Reported side effects are uncommon but may include:

• Mild nausea or stomach upset

• Headache

• Temporary changes in sleep or mood (rare)

Who Should Not Use 7-Keto DHEA Therapy (Contraindications)
This treatment is not appropriate for patients who have:

• Uncontrolled thyroid disorders

• Hormone-sensitive cancers (caution advised)

• Severe liver or kidney disease

• Pregnancy or breastfeeding

Patients must have a yearly in-office consultation with a provider to receive this medication. Currently available only in Nevada, other states TBA.

Pricing:
$159.99 (30 days), 30 capsules

Metformin + Topiramate Therapy: How It Works | Benefits | Safety

Mechanism of Action
At Rolling Wellness, we offer advanced, evidence-based combination therapies to target weight from multiple angles. Metformin + Topiramate is a non-stimulant option that works synergistically to improve metabolism and reduce appetite.

• Metformin lowers glucose production in the liver, improves insulin sensitivity, and stabilizes blood sugar levels. By reducing the insulin spikes that drive fat storage and cravings, it helps the body shift into a more favorable fat-burning state.

• Topiramate works on the brain’s neurotransmitters to suppress appetite, reduce cravings, and enhance satiety. It has also been shown to help reduce compulsive or binge-type eating behaviors.

Together, this dual-acting therapy addresses both metabolic dysfunction and appetite control, offering sustainable results without the stimulant effects of traditional weight-loss medications.

Benefits of Metformin + Topiramate Therapy

• Improves insulin resistance and metabolic health

• Reduces appetite and cravings for greater dietary control

• Non-stimulant option, ideal for patients who cannot tolerate traditional diet pills

• Supports sustainable, long-term weight loss and fat reduction

• May be especially effective for patients with prediabetes, PCOS, or metabolic syndrome

Possible Common Side Effects
Side effects vary but are typically mild and improve with dose adjustment:

• Gastrointestinal upset (more common with Metformin)

• Tingling sensations in hands or feet (paresthesias, more common with Topiramate)

• Metallic taste or changes in taste perception

• Mild fatigue or cognitive “slowing” (rare, dose-dependent with Topiramate)

Your provider will carefully determine the appropriate dosing and titration schedule to maximize benefit while minimizing side effects.

Who Should Not Use Metformin + Topiramate Therapy (Contraindications)
This treatment is not appropriate for patients who have:

• Severe renal or hepatic impairment (contraindication to Metformin)

• History of lactic acidosis

• History of kidney stones or metabolic acidosis (contraindication to Topiramate)

• Pregnancy or breastfeeding

• Known hypersensitivity to Metformin or Topiramate

Pricing:
$149.99 (30 days) 250/5 mg or 250/10 mg